A sample of cloudy cerebrospinal fluid (CSF) from a suspected meningitis case arrives and you are told to Gram stain it and then to plate it on blood agar and chocolate agar. In the Gram stain you find gram negative rods of varying size and shape. You also find a lot of bacteria inside phagocytic cells. They are not diplococcic. Colonies grown on both of the plates you inoculated. Later the charge nurse tells you that the patient a 3-year old girl has not received any childhood vaccinations. 1- What is the most likely causative organism? Why? 2- Why was the childs unvaccinated status helpful in the diagnosis? Explain. 3- What is causing the cloudiness in the CSF? Explain. 4- What other types of infection can this organism cause in children? Explain. What is herd immunity? Discuss it in relation to this case. Show less
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